Deep-tech product and evidence strategy

Deep scientific products fail when taste is treated as decoration.

In serious life-science products, taste is a technical discipline. It shows up in the data model, the interface, the documentation, the claims, the regulatory posture, the naming, the route structure, the visual system, and the parts of the product most users never see. My work brings that discipline to scientific software, biomedical evidence systems, precision medicine infrastructure, and product-facing research.

What this work resolves

Taste as technical judgement

Scientific products need the same care inside the system as on the visible surface. Data models, routes, identifiers, documentation, defaults, and edge cases all shape trust.

Evidence into product

Methods become useful when users can reach a defensible interpretation without assembling evidence manually across fragmented tools, papers, databases, and local scripts.

Trust before claims

Users infer scientific quality from behaviour: stable pages, clear definitions, fast loading, consistent filters, visible provenance, accessible design, and disciplined language.

Commercial seriousness

Naming, trademarks, ownership, domains, documentation, SEO, support, pricing, and licensing affect whether a useful scientific product can survive beyond the first release.

Evidence at a glance

Bench to product experience from molecular biology and disease discovery to software, product design, regulation, and adoption
Successful products public scientific technologies spanning statistical evidence, genomics, visualisation, reporting, and infrastructure
Market design institutional and product identities, including Switzerland Omics, SwissPedHealth, and Swiss Genomics Association
Full product chain naming, domain strategy, UX, data architecture, documentation, IP, regulation, distribution, and commercial model

Portfolio samples

Product strategy and design systems

Product judgement

Product positioning, user needs, workflow design, feature discipline, adoption logic, pricing layers, commercial model, product taxonomy, and release communication.

Scientific UX

Search-first workflows, result ranking, filter logic, linked molecular context, structure viewing, table behaviour, state preservation, accessibility, and inspectable evidence.

Evidence architecture

Data provenance, field definitions, score meaning, versioned sources, stable identifiers, linked records, uncertainty, claim structure, and reproducible interpretation.

Technical architecture

Next.js, React, TypeScript, Tailwind, R, Python, SQL, PostgreSQL, APIs, server routes, modular components, secure access, caching, logging, and scalable data systems.

Trust and governance

IP review, trademark logic, domain strategy, ownership checks, documentation discipline, regulated claims, auditability, quality language, and lifecycle maintenance.

Growth and distribution

Search structure, indexable pages, documentation hubs, backlinks, technical content, scientific publishing, LinkedIn distribution, usage signals, and institutional credibility.

Selected product examples

  • Switzerland Omics: scientific product identity, technical writing, regulatory positioning, and product architecture for probabilistic genomics and biomedical evidence systems.

  • Genomic Vault: secure genomic custody and controlled access concept for long-term biomedical data use.

  • Archipelago: Manhattan plots are for GWAS. Archipelago plots are for complex variant association studies, published in Lawless et al (2026). CRAN version CRAN downloads

  • QuantBayes: standardises how evidence strength is expressed - quantifying genomic variant evidence sufficiency with Bayesian posterior intervals, preprinted in Quant Group et al (2025) CRAN version. CRAN downloads Zenodo DOI

  • PanelAppRex AI: harmonised disease-gene panels from structured clinical and genetic queries, preprinted in Quant Group et al (2025). GitHub stars Dataset DOI

  • VCFheader: parsing VCF headers and generating structured standalone HTML reports, described in Lawless (2026). CRAN version CRAN downloads

Selected publications

ORCID record: ORCID iD 0000-0001-8496-3725

A Bayesian model for quantifying genomic variant evidence sufficiency in Mendelian disease. medRxiv, 2025.

Application of qualifying variants for genomic analysis. Bioinformatics, 42(2), btaf676, 2026.

PanelAppRex aggregates disease gene panels and facilitates sophisticated search. medRxiv, 2025.

Relevant product work

Switzerland Omics · product system

Scientific brand, product architecture, and evidence design

Built a complete scientific product environment for probabilistic genomics, including public positioning, visual language, product taxonomy, regulatory framing, technical writing, and user-facing evidence concepts.

Switzerlandomics.ch, Quant DB, Quant Scan, Quant Calc, Genomic Vault, evidence frameworks, regulatory positioning, product pages, scientific documentation, and market-facing technical communication.

Variant Impact · product design book

Protein variant interpretation as a complete product system

Designed the product logic for a web system that connects missense variant prediction, protein structure, functional annotation, and molecular context into one navigable interpretation workflow.

Naming, positioning, canonical domain strategy, UX, search logic, route structure, data model, UniProt, gnomAD, AlphaFold, ClinVar, MANE, documentation, security, cost control, IP, regulation, SEO, and commercial model.

Scientific software · public tools

Methods translated into usable scientific products

Developed software and data products that give statistical and biomedical methods a clear visual, conceptual, and operational form.

Archipelago, QuantBayes, VCFheader, PanelAppRex AI, Qualifying variant database, IEI genetics database, CRAN releases, structured HTML reports, YAML criteria, and publication-linked software.

Institutional identity · trust and adoption

Public-facing biomedical systems with institutional credibility

Built or shaped public identities for scientific and clinical initiatives where clarity, restraint, governance, and trust matter more than novelty.

SwissPedHealth, Swiss Genomics Association, Switzerland Omics, collaborator-facing communication, clinical research positioning, biomedical infrastructure messaging, and high-trust public presentation.

Working fit

Deep-tech teams need taste as much as technical depth. The useful output is a product where the science, data model, interface, documentation, claims, regulation, and commercial path all feel like one coherent system. If you want to build that kind of product, get in touch.